Dental anomalies in individuals with osteogenesis imperfecta: a systematic review and meta-analysis of prevalence and comparative studies

Abstract Background Osteogenesis imperfecta (OI) is a rare genetic disorder primarily caused by mutations in the genes involved in the production of type 1 collagen. OI is also known as brittle bone disease. Objective This study aims to describe the prevalence of dental anomalies (except dentinogenesis imperfecta) in individuals with OI, and compare the prevalence of dental anomalies between individuals with and without OI and between individuals with different types of OI. Search methods Searches in PubMed, Web of Science, Scopus, Ovid, and gray literature were performed in October 2022. Selection criteria Observational studies (with or without a comparison group) that evaluated the prevalence of dental anomalies in individuals with OI. Data collection and analysis: Data items were extracted by two authors. Quality assessment employing the Joanna Briggs Institute checklists and meta-analyses was conducted. Results were provided in prevalence values and odds ratio (OR) / 95% confidence interval (CI). Strength of evidence was determined. Results Eighteen studies were included. Most prevalent dental anomalies in individuals with OI included pulp obliteration (46.4%), dental impaction (33.5%), dental impaction of second molars (27%), and tooth agenesis (23.9%). Individuals with OI type III/IV had 20.16-fold greater chance of exhibiting tooth discoloration in comparison with individuals with OI type I (CI: 1.10-370.98). In comparison with the group without OI, the individuals with OI had 6.90-fold greater chance of exhibiting dental impaction (CI: 1.54-31.00). High methodological quality was found in 47% of the studies. Strength of evidence was low or very low. Conclusions Pulp obliteration, dental impaction, and tooth agenesis were the most prevalent dental anomalies in the OI group. Individuals with OI were more likely to have dental impaction than individuals without OI. Individuals with OI type III/IV (severe-moderate) are more likely to have tooth discoloration than individuals with OI type I (mild).

Hallazgos en radiografías panorámicas de niños entre 6 y 15 años en un hospital odontológico en Argentina / Findings in panoramic radiographs of children between 6 and 15 years at a dental hospital in Argentina

Objetivo: Describir la frecuencia y localización de pato- logías y anomalías dentarias (anomalías de número, tumores, quistes y piezas retenidas) observadas en radiografías pa- norámicas de pacientes pediátricos de entre 6 y 15 años del Hospital Zonal Especializado en Odontología Infantil "Dr. A. Bollini" de la ciudad de La Plata. Materiales y métodos: Se realizó un estudio observa- cional descriptivo de 300 radiografías panorámicas, de niños (n=150) y niñas (n=150) de entre 6 y 15 años, seleccionadas aleatoriamente en el área de radiología del hospital, tomadas en el período comprendido entre marzo de 2018 y marzo de 2020. Los datos obtenidos se volcaron en planillas de cálculo y con ellos se realizó un análisis estadístico descriptivo. Se utilizaron las siguientes variables: edad, sexo, tipo de ano- malía o patología (anomalías de número, tumores, quistes y piezas retenidas), pieza dentaria y ubicación (maxilar o man- díbula). Resultados: Dentro de las anomalías registradas (n=147), se encontraron en mayor medida piezas dentarias retenidas, en un 44,22% de los casos (n=65), agenesias en un 42,18% de los casos (n=62) y supernumerarios en un 13,61% de los casos (n=20). No se hallaron quistes ni tumores. Conclusión: En un 24% de las radiografías panorámicas de niños entre 6 y 15 años se halló alguna anomalía dentaria. Las anomalías más frecuentes fueron piezas dentarias reteni- das y agenesias (AU)

Aim: To describe the frequency and location of dental pathologies and anomalies (number anomalies, tumors, cysts and retained dental pieces) observed in panoramic radio- graphs of pediatric patients between 6 and 15 years of age from the Hospital Especializado en Odontología Infantil "Dr. A. Bollini" from the city of La Plata. Materials and methods: A descriptive observational study was performed based on 300 panoramic radiographs of children (150 girls and 150 boys) between 6 and 15 years old, randomly selected in the Radiology area of the hospital, taken in the period between March 2018 and March 2020. The data obtained were entered into spreadsheets and a descriptive sta- tistical analysis was carried out. The following variables were evaluated: age, sex, type of anomaly or pathology (anomalies of number, tumor, cysts and retained dental pieces), dental piece and location (maxilla or mandible). Results: Among the registered anomalies (n=147), re- tained dental pieces were found to a greater extent, in 44.22% of the cases (n=65), agenesis in 42.18% of the cases (n=62) and supernumeraries in 13.61% of the cases (n=20). No cysts or tumors were found. Conclusion: In 24% of panoramic radiographs of chil- dren between 6 and 15 years old, some dental anomaly was found. The most frequent anomalies were retained dental pieces and agenesis (AU)

Evaluación del taurodontismo en radiografías panorámicas en una población peruana / Evaluation of taurodontism in panoramic radiographies in a Peruvian population

RESUMEN El taurodontismo es una alteración en la morfología dentaria, la cual tiene implicancias clínicas en diferentes áreas de la odontología. Objetivo: Evaluar el taurodontismo en radiografías panorámicas en una población peruana. Material y métodos: Se evaluaron 220 radiografías panorámicas digitales en las que se clasificó el tipo de taurodontismo en primeros molares permanentes según el método de Shifman y Chanannel. Las observaciones fueron registradas en una ficha de datos. Resultados: El 51% pertenecieron al sexo masculino y el 49 % al femenino. La frecuencia de taurodontismo según sexo, fue mayor en hombres en 24%, y en mujeres fue 20%. El tipo de taurodontismo más frecuente fue el hipotaurodontismo en un 80%. La localización y la primera molar más frecuente fue el maxilar superior con un 68% y la molar superior izquierda con un 37%, respectivamente. Conclusión: La evaluación de taurodontismo en radiografías panorámicas digitales se caracterizó por ser más frecuente en hombres, en cuanto al tipo y localización resultó ser más frecuente el hipotaurodontismo y maxilar superior respectivamente. Además, se caracterizó por ser más frecuente en los primeros molares superiores del lado izquierdo.

ABSTRACT Taurodontism is a dental anomaly, so it has clinical implications in different areas of dentistry. Objective: To evaluate taurodontism in panoramic radiographs in a Peruvian population. Material and methods: 220 digital panoramic radiographs were evaluated in which the type of taurodontism was classified in permanent first molars according to the Shifman and Chanannel method. Observations were recorded on a data sheet. Results: 51% belonged to males and 49% to females. The frequency of taurodontism, according to sex, was higher in men in 24%, and in women it was 20%. The most frequent type of taurodontism was hypotaurodontism in 80%. The most frequent location and first molar was the upper jaw with 68% and the upper left molar with 37%, respectively. Conclusion: The evaluation of taurodontism in digital panoramic radiographs was characterized by being more frequent in men, in terms of type and location, hypotaurodontism and maxilla, respectively, were more frequent. Furthermore, it was characterized by being more frequent in the upper first molars on the left side.

Prevalence of Developmental Dental Anomalies Using Digital Panoramic Radiographs in Libyan Dental Patients

ABSTRACT@#Dental anomalies may occur due to the complex interactions among genetic, epigenetic, and environmental factors during dental development. The current study aimed to determine the prevalence and gender significance of developmental dental anomalies (DDA) in dental patients. This was a cross-sectional study of 260 subjects (123 males and 137 females) with an age range of 6–35 years old. Clinical and radiographic examinations were performed to determine the prevalence of anomalies in tooth number, shape, size, position, and structure. Descriptive statistics was performed, the chi-square test was used for analysis and p-value was set at 0.05. The findings showed that 203 subjects (78.1%) had DDA, which included 86 males (33.1%) and 117 females (45%). A significant gender difference was found regarding the prevalence of two anomalies (p < 0.05). The most prevalent anomaly was displacement 51.2%, followed by dilaceration 24.2%. A significant gender difference (p < 0.05) was found regarding hypodontia 16.5% and impaction 14.6%, with more predominant in females. Some anomalies were not observed such as microdontia, dentin dysplasia, ectopic eruption, gemination, and taurodontism. The study concluded that displacement and dilacerations were the common abnormalities. These findings may lead to various dental complications. Therefore, early diagnosis and follow-up observation are required to reduce the potential dental problems. In addition, it is helpful to increase the knowledge of practitioners with regards to DDA and its occurrence. Furthermore, it is good to highlight the importance of early diagnosis of DDA, especially in the mixed dentition, which can lead to reducing the complication of an orthodontic treatment plan.

Prevalence of incidental dental anomalies seen on pre-treatment digital panoramic radiographs of a group of Nigerian orthodontic patients: A retrospective study

Background: Radiographs are used by orthodontists in the diagnosis of malocclusion, treatment planning and monitoring. These usually reveal presence of dental anomalies that may require further assessment and management. Objective: To investigate the prevalence, types and distribution of dental anomalies seen on the orthopantomograms (OPGs) of orthodontic patients at the University of Port-Harcourt Teaching Hospital (UPTH).Methods: This was a retrospective cross-sectional radiographic study of a cohort of orthodontic patients who presented to the Department of Child Dental Health, University of Port Harcourt Teaching Hospital, Rivers State, Nigeria. The data gathered from digital orthopantomograms of the patients was analysed using IBM Statistical Package for Social Sciences (SPSS) Statistics for Windows version 25.0. Results: The study comprised 249 patients with an age range of 5-44years (mean age of 14.6±7.7years) comprising 108 (43.4%) males and 141 (56.6%) females.Seventy (28.1%) [(29, 41.4% males), (41, 58.6% females)] of the patients had at least one dental anomaly. Dental anomalies were commonest (48, 68.6%) within 10-19 years age bracket followed by the 0-9 years age bracket (11, 15.7%). The most frequent dental anomaly was taurodontism (43, 61.4%), followed by congenitally missing teeth (8, 11.4%), supernumerary teeth (5, 7.1%), odontoma (4, 5.7%), peg shaped lateral incisors and transposition (2, 2.9%) respectively. Dental anomalies were more frequent in the maxilla (43, 61.4%). Conclusion: The most common dental anomaly was taurodontism. Anomalies were more frequent in female than male patients and in the maxilla than in the mandible

Frequency of pediatric dentomaxilar anomalies in Orthodontics Barros Luco Trudeau healthcare complex, Chile / Frecuencia de anomalías dentomaxilares pediátricas en ortodoncia perteneciente al complejo asistencial Barros Luco Trudeau, Chile

ABSTRACT Introduction: Dentomaxilar anomalies (DMA) are the third most common oral pathology in Chile. Objective: To determine the frequent of dentomaxilar anomalies observed in patients treated in the Department of Orthodontic of Dental Specialties Service (DSS) belonging to the Barros Luco Trudeau Healthcare Complex, Santiago, Chile. The population belongs to pediatric patients between 5 and 15 years, who have DMA, treated in the southern metropolitan health service. Method: The sample of 250 patients with DMA was chosen from April to September of the year 2019, therefore, the data was extracted from the clinical records of the patients. The classification of the anomalies was carried out using the Bonn's biogenetic method, modified by the University of Chile. Result: It was observed that the most frequent intermaxillary DMA of the sample is in the transverse direction and corresponds to the unilateral crossbite, on the other hand, the most frequent intramaxillary DMA is the alteration of dentoalveolar per large tooth. All intermaxillary DMA agreed to be more frequent at the age of 9 years. Conclusion: It was possible to define the frequency of the DMA in patients treated in the DSS, this being in the transverse direction, corresponding to unilateral crossbite. With the present study it is intended to make a contribution for future studies that use similar methodologies.

RESUMEN Introducción: Las anomalías dentomaxilares (ADM) son la tercera patología bucal más frecuente en Chile. Objetivo: Determinar la distribución de frecuencia de anomalías dentomaxilares observadas en los pacientes atendidos por el Departamento de Ortodoncia dentro del Servicio de Especialidades Odontológicas (SEO) perteneciente al Complejo Asistencial Barros Luco Trudeau, Santiago de Chile. La población pertenece a pacientes pediátricos entre 5 y 15 años de edad que presentan ADM, atendidos dentro del servicio de salud metropolitano sur. Método: La muestra de 250 pacientes con ADM fué recolectada a partir del mes de abril a septiembre del año 2019, por lo tanto, es una muestra por conveniencia, los datos fueron extraídos de las fichas clínicas de los pacientes. La clasificación de las anomalías estudiadas fue realizada mediante la clasificación biogenética de Bonn modificada por la cátedra de la Universidad de Chile. Resultado: Se observó que la ADM intermaxilar más frecuente de la muestra es en el sentido transversal y corresponde en el espacio lateral a la mordida cruzada unilateral, por otra parte, la ADM intramaxilar más frecuente es la alteración de tamaño dentoalveolar por diente grande. Todas las ADM intermaxilares coincidieron en ser más frecuentes a la edad de 9 años. Conclusión: Se logró determinar la distribución de las frecuencias de ADM en pacientes atendidos dentro del SEO, siendo esta en el sentido transversal, correspondiente a mordida cruzada unilateral. Con el presente estudio se pretende hacer una contribución para futuros estudios que utilicen metodologías similares.

Dental Rehabilitation of a Rare Hallermann-Streiff Syndrome with Olygodontia: A Case Report / Rehabilitación dental de un caso raro de Síndrome de HallermannStreiff con Oligodoncia: Reporte de un caso

Abstract Hallermann-Streiff syndrome (HSS) is a rare oculomandibulofacial discephaly with hypotrichosis that occurs as a sporadic mutation. It is characterized by abnormal findings especially in head and face. Dental anomalies occur in 50-80% of the patients. In this case report, facial-oral findings and the existing dental anomalies of the syndrome in a 6-year-old male patient diagnosed with HSS were identified. Dental rehabilitation and a 12-month follow-up of the patient were reported. Each case presented with this rare syndrome may contribute to the literature to determine the prognosis of the disease and to take protective and preventive measures.

Resumen El síndrome de Hallermann-Streiff (HSS) es una discefalia oculomandibulofacial rara con hipotricosis que ocurre como una mutación esporádica. Se caracteriza por hallazgos anormales, especialmente en cabeza y cara. Las anomalías dentales ocurren en 50-80% de los pacientes. En este reporte de caso, se identificaron los hallazgos faciales-orales y las anomalías dentales existentes del síndrome en un paciente masculino de 6 años diagnosticado con HSS. Se informó la rehabilitación dental y un seguimiento de 12 meses del paciente. Cada caso presentado con este síndrome raro puede contribuir a la literatura para determinar el pronóstico de la enfermedad y tomar medidas de protección y prevención.

Síndrome Nance-Horan, cataratas congénitas y anomalías dentales / Nance-Horan syndrome, congenital cataracts and dental anomalies

RESUMEN Introducción: La presencia de estructuras dentofaciales atípicas puede ser el primer indicador de otros defectos congénitos relacionados con síndromes también de origen genético. El síndrome Nance-Horan es un trastorno monogénico ligado al cromosoma X, caracterizado fenotípicamente por alteraciones dismorfológicas dentales y craneofaciales distintivas, cataratas congénitas y déficit cognitivo. Objetivo: Describir un caso inusual de anomalías dentarias en el curso del síndrome Nance-Horan. Presentación de caso: Paciente de 13 años de edad, masculino, de piel blanca. Al examen clínico se constató un patrón dismórfico dado por facies alargada y estrecha, orejas prominentes con anteversión de la aurícula, nariz grande con puente nasal alto, diastema generalizado en ambas arcadas, todos los dientes con anomalías de forma y microdónticos. En el estudio radiológico periapical se constataron raíces cortas y cámaras pulpares amplias. Los antecedentes patológicos personales de nuestro paciente, el patrón dismórfico cráneo facial y las radiografías coinciden con características de otros casos de síndrome Nance-Horan reportados en la literatura. La mutación del gen síndrome Nance-Horan se expresa completamente solo en los varones. Como los varones son hemicigóticos para los genes ligados al cromosoma X, basta con una copia del alelo mutado para que aparezca una enfermedad de herencia recesiva ligada al sexo. Conclusiones: Se evidenció que es de crucial importancia realizar un cuidadoso examen, tanto clínico como radiográfico, de los pacientes con anomalías dentales. Se insiste en el trabajo mancomunado entre diferentes disciplinas y especialidades, tanto médicas como estomatológicas(AU)

ABSTRACT Introduction: The presence of atypical dentofacial structures may be the first indicator of other congenital defects related to syndromes of likewise genetic origin. Nance-Horan syndrome is a monogenic X linked disorder phenotypically characterized by distinctive dysmorphic dental and craniofacial alterations, congenital cataracts and cognitive deficit. Objective: Describe an unusual case of dental anomalies in the course of Nance-Horan syndrome. Case presentation: A case is presented of a white male 13-year-old patient. Clinical examination revealed a dysmorphic pattern characterized by long narrow facies, prominent ears with auricular anteversion, a big nose with a high nasal bridge, generalized diastema in both arches, and all the teeth microdontic and abnormally shaped. Periapical radiological examination found short roots and broad pulp chambers. The personal pathological antecedents of the patient, the dysmorphic craniofacial pattern and the radiographs correspond to characteristics of other cases of Nance-Horan syndrome reported in the literature. Mutation of the Nance-Horan syndrome gene is completely expressed only in males. Since males are hemizygous for X linked genes, one copy of the mutated allele is sufficient for the appearance of a sex-linked recessive inheritance disease. Conclusions: Evidence was found of the crucial importance of conducting careful examination, both clinical and radiographic, of patients with dental anomalies. Emphasis is placed on the joint work of various disciplines and specialties, both medical and dental(AU)

Dens in dente Tipo III A: relato de caso / Dens invaginatus type III A: case report

Introdução: dens in dente é uma anomalia rara de desenvolvimento, caracterizada pela invaginação dos tecidos dentários, podendo variar de um ligeiro aumento da fosseta do cíngulo a um profundo sulco, que pode se estender até o ápice dentário. Objetivo: o objetivo do presente artigo foi relatar um caso clínico e descrever as peculiaridades dos achados clínicos e radiográficos de um dens in dente Tipo III A, com ênfase na descrição de sua morfologia completamente atípica, além das dificuldades que foram encontradas no diagnóstico e durante o tratamento endodôntico. Caso clínico: o paciente compareceu ao ambulatório de uma clínica de Endodontia com queixa de dor e leve edema. Ao exame clínico e radiográfico, observou-se imagem sugestiva de dens in dente no elemento #22, sendo, então, proposto tratamento endodôntico convencional, com estudo tomográfico. Resultados: após 1 ano e 6 meses de acompanhamento, o paciente encontrava-se assintomático. Notou-se reparo satisfatório, com formação óssea, apesar da sobre-extensão do cone. Conclusão: foi possível perceber a importância da tomografia computadorizada de feixe cônico como auxiliar no diagnóstico e planejamento da conduta frente a casos de dens in dente, principalmente por aumentar as chances de sucesso, evitando a perda precoce de elementos dentários (AU).

Introduction: Dens invaginatus is a rare dental anomalycharacterized by invagination of dental tissues, which maybe from a slight increase in the pit of the cingulum to a deep groove that may extend to the tooth apex. This report describes clinical and radiographic findings and the morphology of a completely atypical and unique anomaly, and discusses the difficulties in the diagnosis and endodontic treatment of the root canal of teeth with this complex anatomy. Clinical case: Patient seen in the outpatient clinic of the Endodontic Service with a complaint of pain and mild edema. Clinical and radiographic examinations were suggestive of invagination itooth #22, and conservative endodontic treatment and CT scans were indicated. Results: Patient was asymptomatic and had no functional disorders at 18 months of follow-up. Repair and new bone formation were satisfactory, despite cone overextension. Conclusion: Cone-beam CT seems to be an important method of diagnosis and treatment planning in cases of dens invaginatus, especially because it increases the chances of treatment success and prevents the early loss of teeth (AU).

Displasia ectodérmica hipohidrótica tipo 1 ligada al cromosoma X, síndrome de Christ-Siemens-Touraine: caso clínico y revisión de la literatura / Type 1 hypohidrotic ectodermal dysplasia X-linked, the Christ-Siemens-Touraine syndrome: a clinical case and review of the literature

La displasia ectodérmica hipohidrótica tipo 1 ligada al X (DEH1-X) ­síndrome de Christ-Siemens-Touraine­ es una genodermatosis que forma parte de las displasias ectodérmicas, caracterizadas por alteraciones en el desarrollo de una o más estructuras derivadas de ectodermo. Clínicamente presenta hipotricosis, hipohidrosis e hipodontia de severidad variable. Propósito: Describir las características clínicas de la DEH1-X, su manejo odontológico y diferenciarla de otras entidades patológicas. Caso clínico: Paciente masculino de 18 años de edad, con antecedente familiar de displasia ectodérmica hipohidrótica diagnosticada también en un hermano menor. Acude a consulta por prótesis anterior fracturada y mal ajustada. Se trató mediante frenilectomía anterior y rehabilitación bucal protésica. Discusión: En el diagnóstico y tratamiento de las alteraciones congénitas de desarrollo es de particular importancia la identificación temprana y el trabajo en equipo multidisciplinario. El plan de tratamiento y manejo clínico de tejidos orales blandos y duros debe ser adaptado a las necesidades particulares del padecimiento, lo que permitirá establecer un mejor pronóstico. Conclusiones: La DEH1-X es una alteración congénita del desarrollo que afecta estructuras orales, por lo que debe ser identificada por el estomatólogo para atender correctamente las alteraciones dentales y evitar complicaciones posteriores (AU)

Type 1 hypohidrotic ectodermal dysplasia X-linked (DEH1-X) -Christ-Siemens-Touraine syndrome- is a genodermatosis. Ectodermal dysplasias are characterized by development alterations on one or more ectodermal derived structures. IN DEH1-X, patients present hypotrichosis, hypohidrosis and hypodontia of variable severity. Aims: To describe anatomic and clinical characteristics of the DEH1-X, dental treatment, and to differentiate from other clinical conditions. Case report: Male teenager, 18-year-old, was referred for replacement of anterior dental prosthesis. Family history for hypohidrotic ectodermal dysplasia was positive, younger brother with the same condition. Treatment consisted of anterior labial frenectomy and dental prosthetic rehabilitation with acceptable clinical and esthetic's results. Discussion: When diagnosing and treating patients with developmental genetic conditions is particularly important the early detection and the participation of interdisciplinary team work. The clinical treatment of hard and soft tissues of the oral cavity has to be planned and personalized according to the particular needing of each case, in order to achieve better results and long term prognosis. Conclusions: DEH1-X is a congenital developmental disorder, which affects oral structures, should be identified and treated appropriately by the dentist to prevent further dental complications (AU)

Assessing Validity of Printed Panoramic Radiographs Films for Dental Anomaly Detection

@#Introduction: The interpretations of printed panoramic radiographs film frequently depend on personal judgements analysis by observers. The findings correlations between more than two observers must consider statistical tool which can determine that sometimes the observers will agree or disagree merely by chance. Intraclass Correlation Coefficient (ICC) generally measures the degree of similarity among individuals within a cluster. Kappa statistic is the most frequently applied statistical analysis for this reason. This study aims to determine the validity of utilising printed panoramic radiographs for assessing dental anomalies and inter-examiner reliability in detecting dental anomalies observed within the panoramic radiographs. Methods: Twenty samples of printed versions of orthopantomogram (OPG) were arbitrarily selected from the AMDI Dental Clinic. Radiographic analyses were conducted twice, Trial 1 and Trial 2, with two-week intervals in between. Ten (10) printed OPG films were used in each session. During both assessments, incidence of dental anomalies was determined. All twenty OPGs were examined and analysed by the principal investigator and two independent examiners according to the inclusion and exclusion criterias. The data analysis was carried out using SPSS version 23. Results: The results of ICC for Trials 1 and 2 were 0.961 and 0.984, respectively. Conclusion: The outcomes demonstrated that the printed OPG films can be used to detect dental anomalies and inter-examiner dependability was in very good assertion for both trials, hence printed OPG films that satisfy the inclusion and exclusion criterias can be utilised for assessing dental anomalies as shown by the reliable ICC values in this study.

Dental Management in a Patient with Turner Syndrome with Dental Anomalies: A Case Report / 대한소아치과학회지

Turner syndrome (TS) is a chromosomal disorder caused by monosomy of the X chromosome, with complete or partial absence of the second sex chromosome. Anomalies of root morphology have been found to occur more often in patients with TS, which make endodontic treatment challenging and requires special handling. The patients with TS may also have systematic problems such as cardiac or renal malformations, so in treating these patients it is important for clinicians not only to be aware of the characteristic intraoral findings, but also to make the patients have regular dental check-ups to prevent oral complications in advance.An 12-year-old girl who had been diagnosed with TS at the age of 10 years was referred due to discomfort in the bilateral mandibular premolar regions. Dens evaginatus and taurodontism were detected in all the mandibular premolars characteristically. The bilateral mandibular first premolars had three roots and the bilateral mandibular second premolars had periapical lesion with two roots. Due to the complexity of the root canal anatomy, root canal treatment were completed with a dental microscope to ensure adequate visualization. After 2 years of regular follow-up examinations, there were no clinical sign or symptom associated with the teeth, and no periapical lesion, was found.This case report describes the characteristic oral features and dental management of TS patients.

Caracterización de la enseñanza-aprendizaje del diagnóstico de anomalías dentomaxilofaciales en Sancti Spíritus. 2016 / Characterization of teaching-learning of the diagnosis of dentomaxillofacial anomalies in Sancti Spíritus. 2016

Fundamento: El diagnóstico de anomalías dentomaxilofaciales es una de las funciones del estomatólogo general, de allí la importancia de su enseñanza-aprendizaje con enfoque desarrollador. Objetivo: Caracterizar la enseñanza-aprendizaje del diagnóstico de anomalías dentomaxilofaciales en Sancti Spíritus. Metodología: Se realizó un estudio descriptivo transversal en la Universidad de Ciencias Médicas de Sancti Spíritus, se seleccionó una población de 6 profesores y 32 estudiantes de cuarto año de la carrera Estomatología en el curso 2014-2015. Se emplearon métodos del nivel teórico, empírico y estadístico con procedimientos matemáticos. Resultados: Predominó el reconocimiento por parte de estudiantes y profesores de la importancia de este contenido en la asignatura Ortodoncia de la carrera Estomatología, existe experiencia de los profesores, prevaleció la educación en el trabajo entre las formas organizativas del trabajo docente, concurren limitaciones para utilizar el diagnóstico pedagógico, precisar los objetivos, estructurar y controlar los contenidos en correspondencia con el método clínico, aplicar alternativas, lograr la implicación activa de los estudiantes durante las tareas docentes y, no siempre se realiza en relación con el contexto laboral del futuro profesional. Conclusiones: A pesar de haber fortalezas para la enseñanza-aprendizaje del diagnóstico de anomalías dentomaxilofaciales, se identificaron limitaciones que la alejan del enfoque desarrollador que debe caracterizar la didáctica contemporánea. Palabras clave: Ortodoncia, diagnóstico clínico, anomalías maxilofaciales, anomalías dentarias, educación en odontología

Hallazgos incidentales en ortopantomografías maxilomandibulares de pacientes adultos jóvenes / Incidental findings on panoramic radiographs of the maxilla and mandible of young adult patients

Introducción: la valoración radiográfica rutinaria en la práctica odontológicaes esencial para un adecuado diagnóstico y plan de tratamiento. Laortopantomografía o radiografía panorámica es una técnica simple, rápida, de bajo costo y a una baja dosis de radiación. Objetivos: Caracterizarlos hallazgos incidentales más comunes en radiografías panorámicas de pacientes adultos jóvenes de una clínica dental universitaria. Materialy métodos: Se realizó un estudio descriptivo, retrospectivo, de cortetransversal de radiografías panorámicas digitales, tomadas e interpretadas de manera ciega, explorando alteraciones óseas y anomalías dentales. Se realizó la caracterización de su presentación por género de los participantes. Para el análisis de datos se utilizaron pruebas no paramétricas (la prueba χ2, exacta de Fisher y binomial). Resultados: Se tomaron 98 radiografías del mismo número de pacientes, con edad promedio de 19.45 años, predominando las mujeres (69/70.40 por ciento), solteros (94/95.91 por ciento) y de zona urbana (77/78.57 por ciento). Existieron 387 alteraciones, 268 (69.25 por ciento) enmujeres, y 119 (30.74 por ciento) en hombres, con un promedio de 3.88 y 4.10 alteraciones por paciente, respectivamente. La distribución mostró en total 122 (31.52 por ciento) lesiones a nivel de senos maxilares, 124 (32.04 por ciento) en fosasnasales, 16 (4.13 por ciento) lesiones radiolúcidas u opacas, y 125 (32.29 por ciento) anomalías asociadas a retención dental. La comparación de acuerdo al género mostró diferencia (p ≤ 0.001) en la frecuencia de alteraciones, en todos los casos determinada por las mujeres, para cada sitio y tipo de lesión presentada. Conclusiones: El valor de la radiografía panorámica para detectar anomalías de estructuras orofaciales demostró en este estudio su utilidad en la práctica asistencial desde una perspectiva epidemiológica.

Background: doutine dental X-Ray assessment in dental practice isessential for proper diagnosis and treatment. Orthopantomographyor panoramic radiography is a quick, simple, low-cost, and low-doseradiation technique. Objective: To describe the most common incidentalfi ndings on the panoramic radiographs of young adult patients ata university dental clinic. Material and methods: A descriptive,retrospective, cross-sectional study was carried out, in which digitalpanoramic radiographs were taken and interpreted blindly to examinebone disorders, and dental anomalies, and the prevalence of theseaccording to the gender of the participants. Nonparametric statistics(Chi-square χ2, Fisher’s exact, and binomial tests) were used for dataanalysis. Results: 98 radiographs were taken of the same number ofpatients with a mean age of 19.45 years, most of whom were women(69/70.40%), single (94/95.91%), and from urban areas (77/78.57%). 387alterations were found, 268 (69.25%) in women and 119 (30.74%) in men,with an average of 3.88 and 4.10 alterations per patient, respectively. Thedistribution presented a total of 122 (31.52 %) lesions in the maxillarysinus, 124 (32.04 %) in the nostrils, 16 (4.13 %) radiolucent or opaquelesions, and 125 (32.29%) anomalies associated with tooth retention. Acomparison by sex revealed a diff erence (p < 0.001) in the frequency ofalterations, which was greater in women for all sites and types of lesion.Conclusions: The study showed the usefulness of panoramic radiographyin clinical practice to detect anomalies of the orofacial structure from anepidemiological perspective.

Teratogenicity of Antiepileptic Drugs

OBJECTIVE: Antiepileptic drugs (AED) have chronic teratogenic effects, the most common of which are congenital heart disease, cleft lip/palate, urogenital and neural tube defects. The aim of our study is to examine teratogenic effects of AED and the correlation between these malformations and AED in single or multiple pregnancies. METHODS: This is a retrospective study of malformations in children born to mothers currently followed up by our outpatient clinics who used or discontinued AED during their pregnancy. Their children were then investigated using echocardiography, urinary ultrasound, cranial magnetic resonance image, and examined by geneticists and pediatric dentists. RESULTS: One hundred and seventeen children were included in the study. Ninety one of these children were exposed to AED during pregnancy. The most commonly used AED were valproic acid and carbamazepine in monotherapy. The percentage of major anomaly was 6.8% in all children. Dysmorphic features and dental anomalies were observed more in children exposed especially to valproic acid. There were 26 mothers with two and four mothers with three pregnancies from the same fathers. No correlation was found between the distribution of malformations in recurring pregnancies and AED usage. CONCLUSION: Our study has the highest number of dysmorphism examined in literature, found in all the children exposed to valproic acid, which may account for the higher rate of facial dysmorphism and dental anomalies. On lower doses of valproic acid, major malformations are not seen, although the risk increases with polytherapy. Our data also indicate possible effects of genetic and environmental factors on malformations.

Dental anomalies in an orthodontic patient population with maxillary lateral incisor agenesis

ABSTRACT Introduction: The purpose of this study was to evaluate the prevalence of dental anomalies in a subpopulation of orthodontic patients with agenesis of maxillary lateral incisors (MLI). Methods: The material of the present study included the records of the 1964 orthodontic patients. Panoramic radiographs and dental casts were used to analyze other associated eight dental anomalies, including agenesis of other teeth, dens invaginatus, dens evaginatus, peg shaped MLI, taurodontism, pulp stone, root dilaceration and maxillary canine impaction. Results: Out of the 1964 patients examined, 90 were found to have agenesis of MLI, representing a prevalence of 4.6%. The most commonly found associated-anomalies were agenesis of other teeth (23.3%), peg-shaped MLIs (15.6%), taurodontism (42.2%), and dilacerated teeth (18.9%). Conclusion: Permanent tooth agenesis, taurodontism, peg-shaped maxillary lateral incisor, and root dilacerations are frequently associated with maxillary lateral incisor agenesis.

RESUMO Objetivo: o objetivo do presente estudo foi avaliar a prevalência de anomalias dentárias em uma subpopulação de pacientes ortodônticos com agenesia de incisivos laterais superiores (ILS). Material e Métodos: o material do presente estudo incluiu os registros de 1964 pacientes ortodônticos. Radiografias panorâmicas e modelos de estudo foram usados para analisar outras anomalias dentárias associadas, incluindo a agenesia de outros dentes, dens invaginatus, dens evaginatus, ILS conoides, taurodontismo, calcificação pulpar, dilaceração radicular e impacção do canino superior. Resultados: dos 1964 pacientes examinados, constatou-se que 90 tinham agenesia do ILS, o que representa uma prevalência de 4,6%. As anomalias associadas mais comumente encontradas foram a agenesia de outros dentes (23,3%), ILS conoides (15,6%), taurodontismo (42,2%) e dentes com dilaceração (18,9%). Conclusão: a agenesia de dentes permanentes, o taurodontismo, incisivos laterais superiores conoides e dilaceração radicular estão frequentemente associados à agenesia de incisivos laterais superiores.

Agenesias múltiplas e microdontia / Multiple agenesis and microdontia ­ a case report

Nowadays, esthetics has guided patients to seek for dental treatment. Tooth development anomalies are an important category of morphologic variations and malocclusions. Tooth agenesis, also described as congenital absence, is characterized by numeric tooth reduction. It is one of the most frequent changes in the human being and originates from disturbances at tooth formation initiation and proliferation, being classified as hipodontia, oligodontia, or anodontia. On the other hand, microdontia is characterized by smaller teeth, involving the entire arch or a tooth group. Conoid or microteeth compromise the smile and lead patients to seek for dental treatment. Microdontia can be seen as a series of histological changes at the epithelial tooth structure during enamel organ formation, with the final tooth smaller than the normal values. As dental professionals, we must guide patients for better treatment ways. This paper aimed to present a clinical case involving multiple tooth agenesis and microdontia, highlightening the etiology, prevalence, and treatment of these anomalies.

Prevalencia de dientes supernumerarios en niños con labio y/o paladar fisurado / Prevalence of supernumerary teeth in children with cleft lip and/or palate

El objetivo del estudio fue conocer la prevalencia de dientes supernumerarios en niños con labio y/o paladar fisurado. Se realizó un estudio transversal, se revisaron 608 ortopantomografías de expedientes de pacientes pediátricos que acuden a las clínicas de estomatología y ortodoncia del Hospital General <

The aim of the present study was to establish the prevalence of supernumerary teeth in children afflicted with cleft lip and/ or palate. A cross-sectioned study was conducted on 608 orthopantomographies from pediatric patients who attended the stomatology and orthodontics clinics of the <

Multidisciplinary Management of Impacted Supernumerary Teeth.

Background: Mesiodens are supernumerary teeth present in the anterior maxillary region that may erupt or remain embedded in the jawbone. The incidence of mesiodens is rare, surgical removal of supernumerary teeth with correction of anterior teeth by orthodontic treatment is performed. Case Report: This case report represents a very rare incidence of multiple mesiodens in a male patient. Extraction of two mesiodens was indicated, as these impacted supernumerary teeth may cause complications during orthodontic treatment. The third tooth was not operated on the fact that it needs to be extracted by additional extraoral approach involving risk factors. The current case report delineates the fruitful administration of the un-erupted supernumerary teeth situated high in the mid-palatal area not associated with any syndrome. Blends of operating and surgical strategies were utilized to enhance the results with hard and soft tissue conservation, maintenance and support. In the surgical phase, surgical removal of the supernumerary teeth, bone grafting was done using the hydroxyapatite. Radiographic evidence of complete healing was observed following up visit. Conclusion: Timely diagnosis and suitable management can decrease the potential complications due to the presence of supernumerary teeth. Dental clinicians should be aware of related clinical signs and must look for unexpected findings during the routine clinical as well radiological examinations.

Common Dental Anomalies in Cleft Lip and Palate Patients

Background: Cleft lip and palate (CLP) is the most common orofacial congenital malformation in live births. CLP can occur individually or in combination with other congenital deformities. Affected patients experience a number of dental, aesthetic, speech, hearing, and psychological complications and have a higher incidence of severe dental conditions. The purpose of this study is to characterise the different types of dental anomalies that are frequently associated with CLP patients based on a literature survey. Methods: By literature survey, this study characterises the different types of dental anomalies that are frequently associated with cleft lip and palate patients. Results: Common dental anomalies associated with CLP are supernumerary tooth, congenitally missing tooth, delayed tooth development, morphological anomalies in both deciduous and permanent dentition, delayed eruption of permanent maxillary incisors, microdontia, and abnormal tooth number. Conclusion: The incidence of certain dental anomalies is strongly correlated with Cleft lip and palate, a finding that is consistent with previous studies.